Abstract:
Diabetes is a chronic, metabolic disease characterized by elevated levels of blood glucose which leads over time to serious damage to the heart, blood vessels, eyes, kidneys and nerves. These problems can be avoided with proper diabetes management and early detection. The large number of populations especially in remote areas face the challenges of knowing early the disease before symptoms develop. To address challenges associated with traditional diagnostic methods, such as time-consuming processes, cost, complexity and limited accessibility, portable microfluidic devices have significantly enhanced the delivery of healthcare services, particularly in remote or resource-limited settings to automatically detect and monitor glucose levels in urine and blood for providing rapid and accurate results. This thesis explores the utilization of Rasberry Pi microcontroller with microfluidic platforms, GSM, to develop a sensitive, accurate and costeffective solution for frequent diabetes detection and monitoring in home environments and utilized by those who are not healthcare professionals. This research combines a number of elements including microchannels, Biosensors, and data processing modules into a portable and approachable platform. The device uses small samples of urine, blood and sensing techniques. Our approach began with utilizing a 3D printer, employing Polydimethylsiloxane (PDMS), to design and prototype a microfluidic chip. Enhancing its functionality, we seamlessly integrated a biosensor capable of detecting diabetes-related biomarkers. Finally, we tested a device with different samples for analyzing the performance of the device. The outcomes of this study significantly contribute to mitigating risks associated with complications by enabling the convenient monitoring of blood glucose levels at home, empowering non-medically trained individuals. Moreover, our research offers promising avenues for reducing healthcare expenditures by alleviating the necessity for frequent hospital visits for blood glucose tests.
